Symptom Dimensions of Depression and Apathy and Their Relationship With Cognition in Parkinson's Disease.

ABSTRACT:

Objectives

Both depression and apathy, alone and in combination, have been shown to negatively affect cognition in patients with Parkinson's disease (PD). However, the influence of specific symptom dimensions of depression and apathy on cognition is not well understood. The current study investigated the relationship between symptom dimensions of depression and apathy, based on factors identified in Kirsch-Darrow et al. (2011), and memory and executive function in PD.

Methods

A sample of 138 non-demented individuals with PD (mean age=64.51±7.43 years) underwent neuropsychological testing and completed the Beck Depression Inventory, 2nd Edition, and Apathy Scale. Separate hierarchical regression models examined the relationship between symptom dimensions of depression and apa

SUBMITTER: Szymkowicz SM 

PROVIDER: S-EPMC5820218 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature