Compromised Dynamic Cerebral Autoregulation in Patients with Epilepsy.

ABSTRACT:

Objective

The aim of this study is to analyze dynamic cerebral autoregulation (dCA) in patients with epilepsy.

Methods

One hundred patients with epilepsy and 100 age- and sex-matched healthy controls were recruited. Noninvasive continuous cerebral blood flow velocity of the bilateral middle artery and arterial blood pressure were recorded. Transfer function analyses were used to analyze the autoregulatory parameters (phase difference and gain).

Results

The overall phase difference of patients with epilepsy was significantly lower than that of the healthy control group (p = 0.046). Furthermore, patients with interictal slow wave had significant lower phase difference than the slow-wave-free patients (p = 0.012). There was no difference in overall phase be

SUBMITTER: Lv S 

PROVIDER: S-EPMC5820585 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature