Heart rate variability and lifetime risk of cardiovascular disease: the Atherosclerosis Risk in Communities Study.

ABSTRACT:

Purpose

The purpose of this study was to estimate the heart rate variability (HRV)-related lifetime cardiovascular disease (CVD) risk.

Methods

We followed 9744 participants without baseline CVD and used a life-table approach to estimate lifetime CVD risk (coronary heart disease, heart failure, and stroke) from 45 through 85 years according to several HRV measures (the SD of RR intervals [SD_NN], the root mean square of successive differences of successive RR intervals, the mean of all normal RR intervals [mean_NN], low-frequency [LF] and high-frequency [HF] power, and the LF/HF ratio).

Results

During 192,110 person-years of follow-up, we documented 2856 CVD events. Cox regression analyses with the false discovery rate method correction showed indep

SUBMITTER: Kubota Y 

PROVIDER: S-EPMC5821272 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature