Offspring birthweight by gestational age and parental cardiovascular mortality: a population-based cohort study.

ABSTRACT:

Objective

To estimate risk of parental cardiovascular disease mortality by offspring birthweight.

Design

Population-based cohort study.

Setting and population

Norwegian mothers and fathers with singleton births during 1967-2002 were followed until 2009 by linkage to the Norwegian cause of death registry.

Methods

Hazard ratios by offspring absolute birthweight in grams and birthweight adjusted for gestational age (z-score) were calculated using Cox regression and adjusted for parental age at delivery and year of first birth. Stratified analyses on preterm and term births were performed.

Main outcome measures

Maternal and paternal cardiovascular mortality.

Results

We followed 711 726 mothers and 700 212 fathers and found a strong link between matern

SUBMITTER: Morken NH 

PROVIDER: S-EPMC5821431 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature