Scan-rescan of axcaliber, macromolecular tissue volume, and g-ratio in the spinal cord.

ABSTRACT:

Purpose

Recent MRI techniques have been introduced that can extract microstructural information in the white matter, such as the density or macromolecular content. Translating quantitative MRI to the clinic raises many challenges in terms of acquisition strategy, modeling of the MRI signal, artifact corrections, and metric extraction (template registration and partial volume effects). In this work, we investigated the scan-rescan repeatability of several quantitative MRI techniques in the human spinal cord.

Methods

AxCaliber metrics, macromolecular tissue volume, and the fiber g-ratio were estimated in the spinal cord of eight healthy subjects, scanned and rescanned the same day in two different sessions.

Results

Scan-rescan repeatability deviation was 3% for all metr

SUBMITTER: Duval T 

PROVIDER: S-EPMC5821542 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature