A prospective, observational cohort study comparing cancer clinical trial availability and enrollment between early adolescents/young adults and children.

ABSTRACT:

Background

Poor enrollment of adolescents and young adults (AYAs) (ages 15-39 years) onto cancer clinical trials (CCTs) may contribute to inferior survival gains compared with children. In this study, the authors assessed whether differences in CCT availability would explain lower CCT enrollment for early AYAs (eAYAs) (ages 15-21 years).

Methods

This prospective, observational cohort study was conducted at a single academic children's hospital. For consecutive patients who were newly diagnosed with cancer over a 13-month period, it was determined whether an appropriate CCT existed nationally or was available locally and whether enrollment on that CCT occurred. The proportions of eAYAs versus children in each category were compared using the chi-square test. The impact of age

SUBMITTER: Thomas SM 

PROVIDER: S-EPMC5821554 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature