SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts.

ABSTRACT:

Background

There is a pressing need for robust longitudinal cohort studies in the modern treatment era of multiple sclerosis.

Objective

Build a multiple sclerosis (MS) cohort repository to capture the variability of disability accumulation, as well as provide the depth of characterization (clinical, radiologic, genetic, biospecimens) required to adequately model and ultimately predict a patient's course.

Methods

Serially Unified Multicenter Multiple Sclerosis Investigation (SUMMIT) is an international multi-center, prospectively enrolled cohort with over a decade of comprehensive follow-up on more than 1000 patients from two large North American academic MS Centers (Brigham and Women's Hospital (Comprehensive Longitudinal Investigation of Multiple Sclerosis at the Bri

SUBMITTER: Bove R 

PROVIDER: S-EPMC5821573 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature