Physician interpretation of genomic test results and treatment selection.

ABSTRACT:

Background

Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The University of Texas MD Anderson Cancer Center in Houston regarding actionability and the clinical use of test results.

Methods

On a prospective protocol, patients underwent clinical genomic testing for hotspot mutations in 46 or 50 genes. Six months after sequencing, physicians received questionnaires for patients who demonstrated a variant in an actionable gene, investigating their perceptions regarding the actionability of alterations and clinical use of these fi

SUBMITTER: Brusco LL 

PROVIDER: S-EPMC5821595 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature