Maternal Body Mass Index in Early Pregnancy and Risk of Epilepsy in Offspring.

ABSTRACT:

Importance

There is growing concern about the long-term neurologic effects of prenatal exposure to maternal overweight and obesity. The causes of epilepsy are poorly understood and, in more than 60% of the patients, no definitive cause can be determined.

Objectives

To investigate the association between early pregnancy body mass index (BMI) and the risk of childhood epilepsy and examine associations between obesity-related pregnancy and neonatal complications and risks of childhood epilepsy.

Design, setting, and participants

A population-based cohort study of 1 441 623 live single births at 22 or more completed gestational weeks in Sweden from January 1, 1997, to December 31, 2011, was conducted. The diagnosis of epilepsy as well as obesity-related pregnancy and neona

SUBMITTER: Razaz N 

PROVIDER: S-EPMC5822197 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature