Decreased Lung Function and All-Cause Mortality in HIV-infected Individuals.

ABSTRACT:

Rationale

Human immunodeficiency virus (HIV) infection is associated with pulmonary disease and worse lung function, but the relationship of lung function with survival in HIV is unknown.

Objectives

To determine whether lung function is associated with all-cause mortality in HIV-infected individuals.

Methods

HIV-infected participants from cohorts in three locations underwent pre- and post-bronchodilator spirometry and determination of single-breath diffusing capacity of the lung for carbon monoxide (Dl_CO) in 2008-2009, computed tomographic (CT) scanning of the chest for quantitative emphysema and airway measures, and echocardiography for estimated left ventricular systolic and diastolic function and tricuspid regurgitant velocity. Bivariate analysis and mul

SUBMITTER: Gingo MR 

PROVIDER: S-EPMC5822404 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature