Altered functional networks in long-term unilateral hearing loss: A connectome analysis.

ABSTRACT:

Introduction

In neuroimaging studies, long-term unilateral hearing loss (UHL) is associated with functional changes in specific brain regions and connections; however, little is known regarding alterations in the topological organization of whole-brain functional networks and whether these alterations are related to hearing behavior in UHL patients.

Methods

We acquired resting-state fMRI data from 21 patients with UHL caused by acoustic neuromas and 21 matched healthy controls. Whole-brain functional networks were constructed by measuring interregional temporal correlations of 278 brain regions. Alterations in interregional functional connectivity and topological properties (e.g., small-world, efficiency, and nodal centrality) were identified using graph-theory analysis. The

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC5822584 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature