Fusion of piggyBac-like transposons and herpesviruses occurs frequently in teleosts.

ABSTRACT:

Background

Endogenous viral elements play important roles in eukaryotic evolution by giving rise to genetic novelties. Herpesviruses are a large family of DNA viruses, most of which do not have the ability to endogenize into host genomes. Recently, we identified a novel type of endogenous herpesvirus, which we named "Teratorn", from the medaka (Oryzias latipes) genome, in which the herpesvirus is fused with a piggyBac-like DNA transposon, forming a novel mobile element. Teratorn is a unique herpesvirus that retains its viral genes intact and has acquired the endogenized lifestyle by hijacking the transposon system. However, it is unclear how this novel element evolved in the teleost lineage and whether fusion of two mobile elements is a general phenomeno

SUBMITTER: Inoue Y 

PROVIDER: S-EPMC5822658 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature