Second Primary Malignant Neoplasms and Survival in Adolescent and Young Adult Cancer Survivors.

ABSTRACT:

Importance

Although the increased incidence of second primary malignant neoplasms (SPMs) is a well-known late effect after cancer, few studies have compared survival after an SPM to survival of the same cancer occurring as first primary malignant neoplasm (PM) by age.

Objective

To assess the survival impact of SPMs in adolescents and young adults (AYAs) (15-39 years) compared with that of pediatric (<15 years) and older adult (≥40 years) patients with the same SPMs.

Design, setting, and participants

This was a population-based, retrospective cohort study of patients with cancer in 13 Surveillance, Epidemiology and End Results regions in the United States diagnosed from 1992 to 2008 and followed through 2013. Data analysis was performed between June 2016 and January 20

SUBMITTER: Keegan THM 

PROVIDER: S-EPMC5824209 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature