Effect of propranolol on heart rate variability in hyperthyroidism.

ABSTRACT:

Objectives

We aimed to determine the effect of propanolol on heart rate variability (HRV) in hyperthyroidism before antithyroid treatment. This was a before and after study, on ten patients presenting overt hyperthyroidism naïve to treatment. In each patient, a resting electrocardiogram was done followed by estimation of cardiac autonomic dysfunction during five maneuvers (Ewing battery tests). Long term HRV measurement was done using 24 h ambulatory electrocardiographic recording. This automatically provided estimation of HRV using SDNN and RMSSD index, LF, HF, and HF/LF ratio. After baseline investigations, 40 mg of propanolol was given twice a day for 3 days and same parameters were measured after 72 h of treatment.

Results

Our patients were aged 40 ± 10 years. Propanolol

SUBMITTER: Tankeu AT 

PROVIDER: S-EPMC5824553 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature