Body mass index and lung cancer risk: a pooled analysis based on nested case-control studies from four cohort studies.

ABSTRACT:

Background

Obesity has been proposed as a potential protective factor against lung cancer. We examined the association between BMI and lung cancer risk in a pooled analysis based on nested case-control studies from four cohort studies.

Methods

A case-control study was nested within four cohorts in USA, Europe, China and Singapore that included 4172 cases and 8471 control subjects. BMI at baseline was calculated as weight in kilograms divided by height in meters squared (kg/m²), and classified into 4 categories: underweight (BMI < 18.5), normal weight (18.5 ≤ BMI < 25), overweight (25 ≤ BMI < 30) and obese (≥30). Odds ratios (ORs) and 95% confidence intervals (CIs) for BMI-lung cancer associations were estimated using unconditional logistic regression, adjusting fo

SUBMITTER: Sanikini H 

PROVIDER: S-EPMC5824613 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature