Prevalence of nasal colonization and strain concordance in patients with community-associated Staphylococcus aureus skin and soft-tissue infections.

ABSTRACT:

Objective

Determine the prevalence and relatedness of Staphylococcus aureus anterior nares colonization in individuals with community-associated staphylococcal skin and soft-tissue infection (SSTI).

Design

Observational cohort.

Setting

US Army soldiers undergoing infantry training.

Participants

Trainees who developed SSTI from May 2010 to January 2012.

Methods

Participants underwent anterior nares culture at the time of presentation for purulent SSTI. We determined the prevalence of S. aureus nasal colonization and strain relatedness between colonizing and clinical isolates with pulsed-field gel electrophoresis (PFGE).

Results

We enrolled 1,203 SSTI participants, of whom 508 had culture-confirmed S. aureus SSTI. Overall, 70% (357/508) were coloniz

SUBMITTER: Ellis MW 

PROVIDER: S-EPMC5824647 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature