Relationship Between Fibrosis Detected on Late Gadolinium-Enhanced Cardiac Magnetic Resonance and Re-Entrant Activity Assessed With Electrocardiographic Imaging in Human Persistent Atrial Fibrillation.

ABSTRACT:

Objectives

This study sought to assess the relationship between fibrosis and re-entrant activity in persistent atrial fibrillation (AF).

Background

The mechanisms involved in sustaining re-entrant activity during AF are poorly understood.

Methods

Forty-one patients with persistent AF (age 56 ± 12 years; 6 women) were evaluated. High-resolution electrocardiographic imaging (ECGI) was performed during AF by using a 252-chest electrode array, and phase mapping was applied to locate re-entrant activity. Sites of high re-entrant activity were defined as re-entrant regions. Late gadolinium-enhanced (LGE) cardiac magnetic resonance (CMR) was performed at 1.25 × 1.25 × 2.5 mm resolution to characterize atrial fibrosis and measure atrial volumes. The relationship between LGE b

SUBMITTER: Cochet H 

PROVIDER: S-EPMC5824731 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature