Altered task-related modulation of long-range connectivity in children with autism.

ABSTRACT: Functional connectivity differences between children with autism spectrum disorder (ASD) and typically developing children have been described in multiple datasets. However, few studies examine the task-related changes in connectivity in disorder-relevant behavioral paradigms. In this paper, we examined the task-related changes in functional connectivity using EEG and a movement-based paradigm that has behavioral relevance to ASD. Resting-state studies motivated our hypothesis that children with ASD would show a decreased magnitude of functional connectivity during the performance of a motor-control task. Contrary to our initial hypothesis, however, we observed that task-related modulation of functional connectivity in children with ASD was in the direction opposite to that of TDs. The tas

SUBMITTER: Pillai AS 

PROVIDER: S-EPMC5825245 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature