Association of obstructive sleep apnea with hypertension: A systematic review and meta-analysis.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) is a sleep disorder characterized as complete or partial upper airflow cessation during sleep. Although it has been widely accepted that OSA is a risk factor for the development of hypertension, the studies focusing on this topic revealed inconsistent results. We aimed to clarify the association between OSA and hypertension, including essential and medication-resistant hypertension.

Methods

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was followed. PubMed and Embase databases were used for searching the relevant studies published up to December 31, 2016. A quantitative approach of meta-analysis was performed to estimate the pooled odds ratio (OR) and 95% confidence interval (CI).

Results

Twent

SUBMITTER: Hou H 

PROVIDER: S-EPMC5825975 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature