Characterization of KPC-Encoding Plasmids from Enterobacteriaceae Isolated in a Czech Hospital.

ABSTRACT: Ten Enterobacteriaceae isolates collected in a Czech hospital carried bla_KPC-positive plasmids of different sizes (∼30, ∼45, and ∼80 kb). Sequencing revealed three types of plasmids (A to C) with the Tn4401a transposon. Type A plasmids comprised an IncR backbone and a KPC-2-encoding multidrug resistance (MDR) region. Type B plasmids were derivatives of type A plasmids carrying an IncN3-like segment, while type C plasmids were IncP6 plasmids sharing the same KPC-2-encoding MDR region with type A and B plasmids.

SUBMITTER: Kukla R 

PROVIDER: S-EPMC5826142 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature