A Short-Day Photoperiod Delays the Timing of Puberty in Female Mice via Changes in the Kisspeptin System.

ABSTRACT: The reproduction of seasonal breeders is modulated by exposure to light in an interval of 24 h defined as photoperiod. The interruption of reproductive functions in seasonally breeding rodents is accompanied by the suppression of the Kiss1 gene expression, which is known to be essential for reproduction. In non-seasonal male rodents, such as rats and mice, short-day photoperiod (SP) conditions or exogenous melatonin treatment also have anti-gonadotropic effects; however, whether photoperiod is able to modulate the puberty onset or Kiss1 gene expression in mice is unknown. In the present study, we investigated whether photoperiodism influences the sexual maturation of female mice via changes in the kisspeptin system. We observed that SP condition delayed the timing of p

SUBMITTER: Bohlen TM 

PROVIDER: S-EPMC5826198 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature