Vertical Hydrodynamic Focusing and Continuous Acoustofluidic Separation of Particles via Upward Migration.

ABSTRACT: A particle suspended in a fluid within a microfluidic channel experiences a direct acoustic radiation force (ARF) when traveling surface acoustic waves (TSAWs) couple with the fluid at the Rayleigh angle, thus producing two components of the ARF. Most SAW-based microfluidic devices rely on the horizontal component of the ARF to migrate prefocused particles laterally across a microchannel width. Although the magnitude of the vertical component of the ARF is more than twice the magnitude of the horizontal component, it is long ignored due to polydimethylsiloxane (PDMS) microchannel fabrication limitations and difficulties in particle focusing along the vertical direction. In the present work, a single-layered PDMS microfluidic chip is devised for hydrodynamically focusing particles in the ve

SUBMITTER: Ahmed H 

PROVIDER: S-EPMC5827645 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature