Uteroglobin and FLRG concentrations in aqueous humor are associated with age in primary open angle glaucoma patients.

ABSTRACT:

Background

The pathophysiological changes occurring in the trabecular meshwork in primary open angle glaucoma are poorly understood, but are thought to include increased extracellular matrix deposition, trabecular meshwork cell apoptosis, inflammation, trabecular meshwork calcification and altered protein composition of the aqueous humor. Although many proteins are present in aqueous humor, relatively few have been studied extensively, and their potential roles in primary open angle glaucoma are unknown.

Methods

Analyte concentrations in aqueous humor from 19 primary open angle glaucoma and 18 cataract patients were measured using a multiplex immunoassay. Fisher's exact test was used to assess statistical significance between groups, and correlations of analyte concentration

SUBMITTER: Ashworth Briggs EL 

PROVIDER: S-EPMC5828060 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature