VIM-positive Pseudomonas aeruginosa in a large tertiary care hospital: matched case-control studies and a network analysis.

ABSTRACT:

Background

Emergence of multidrug-resistant Pseudomonas aeruginosa is of global concern. We aimed to identify epidemiological relationships, the most common way of transmission, and risk factors for presence of Verona Integron-encoded Metallo-β-lactamase (VIM)-positive P. aeruginosa (VIM-PA).

Methods

We conducted a network analysis and matched case-control studies (1:2:2). Controls were hospital-based and matched with cases for ward, day of admission (control group 1 and 2) and time between admission and the identification of VIM-PA (control group 1). The network was visualized using Cytoscape, and risk factors were determined using conditional logistic regression.

Results

Between August 2003 and April 2015, 144 case patients and 576 control patients wer

SUBMITTER: Voor In 't Holt AF 

PROVIDER: S-EPMC5828133 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature