Intraoperative milrinone versus dobutamine in cardiac surgery patients: a retrospective cohort study on mortality.

ABSTRACT:

Background

Several choices of inotropic therapy are available and used in relation to cardiac surgery. Comparisons are necessary to select optimal therapy. In Denmark, dobutamine and milrinone are the two inotropic agents most commonly used to treat post-bypass low cardiac output syndrome. This study compares all-cause mortality with these drugs.

Methods

In a retrospective observational study we investigated 10,700 consecutive patients undergoing cardiac surgery from 1 April 2006 to 31 December 2013 at Aarhus and Aalborg University Hospitals in the Central and Northern Denmark Region. Prospectively entered data in the Western Danish Heart Registry on intraoperative use of inotropes were used to identify 952 patients treated with milrinone, 418 patients treated with dobutamin

SUBMITTER: Nielsen DV 

PROVIDER: S-EPMC5828330 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature