Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis.

ABSTRACT:

Background

During the past decades, Streptococcus dysgalactiae subspecies equisimilis (SDSE) has been increasingly recognized as an important human pathogen. Osteoarticular infections is one of the predominant disease manifestations of SDSE, but the pathogenetic rationale for its arthritogenicity has yet to be unravelled. We aimed to explore if the rising incidence of osteoarticular infections caused by this pathogen in our region emanated from clonal expansion of strains with enhanced tropism for bone and joint tissue components or orthopaedic implants.

Results

Twenty-nine SDSE-isolates associated with osteoarticular infections were retrospectively identified. Their genomic content and affinity for fibronectin, collagen and stainless steel were compared to 24 temporally and

SUBMITTER: Oppegaard O 

PROVIDER: S-EPMC5828338 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature