Mortality and Allograft Loss Trends Among US Pediatric Kidney Transplant Recipients With and Without Focal Segmental Glomerulosclerosis.

ABSTRACT:

Background

Pediatric patients with focal segmental glomerulosclerosis (FSGS) have high rates of disease recurrence and allograft failure after kidney transplantation, but there are few data for long-term survival posttransplantation.

Study design

Retrospective cohort study.

Setting & participants

12,303 pediatric patients (aged <18 years), including 1,408 (11%) patients with FSGS, who received a first kidney transplant in 1990 through 2009 and were followed up through June 2015 were identified from the US Renal Data System database.

Predictors

Primary cause of end-stage renal disease, FSGS or other.

Outcomes

All-cause patient mortality and allograft loss.

Results

All-cause mortality significantly improved for patients with FSGS who underwent trans

SUBMITTER: Wang CS 

PROVIDER: S-EPMC5828873 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature