Birth weight and the risk of histological subtypes of ovarian and endometrial cancers: Results from the Copenhagen School Health Records Register.

ABSTRACT:

Background

Studies of birth weight associations with ovarian and endometrial cancer risks are limited with inconsistent results, and none has evaluated associations by histologic subtype. We utilized prospectively collected birth weight information to investigate the association with risk of ovarian and endometrial cancers overall and by histologic subtype.

Methods

162,559 girls, born from 1930 to 1989, from the Copenhagen School Health Records Register (CSHRR) were followed prospectively via linkage with the Danish health registers. Ovarian (n=666) and endometrial (n=694) cancers were identified from 1978 to 2014. Cox regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI).

Results

Women with lower (2.0-3.25 vs. 3.26-3.75kg) and higher (3

SUBMITTER: Trabert B 

PROVIDER: S-EPMC5829014 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature