Rearrangement of Actin Microfilaments in the Development of Olfactory Receptor Cells in Fish.

ABSTRACT: At present, it remains poorly understood how the olfactory neuron migrates through the thick neuroepithelium during its maturation from a stem cell and how it develops a specific sensitivity to environmental odorants after maturation. We investigated the cytochemical features associated with the development of olfactory cells before and after the incorporation of dendrites into the surface of the olfactory epithelium. Using cytochemical staining for the actin cytoskeleton and other cell components, we found that immature neurons acquire a streamlined shape that resembles a «hot-dog» during their migration: a dense layer of actin microfilaments forms beneath the surface membrane of the growing dendrite, and the bulk of the nuclear material moves inside this layer. We have found that when th

SUBMITTER: Klimenkov IV 

PROVIDER: S-EPMC5829147 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature