Detecting Glaucomatous Progression With a Region-of-Interest Approach on Optical Coherence Tomography: A Signal-to-Noise Evaluation.

ABSTRACT:

Purpose

To compare two region-of-interest (ROI) approaches and a global thickness approach for capturing progressive circumpapillary retinal nerve fiber layer (cpRNFL) changes on optical coherence tomography (OCT) imaging.

Methods

Progressive cpRNFL thickness changes were evaluated in 164 eyes with a clinical diagnosis of glaucoma or suspected glaucoma; all eyes underwent optic disc OCT imaging on two visits at least 1 year apart. Such changes were evaluated with a manual ROI approach (ROI_M), which involved manual identification of region(s) of observed or suspected glaucomatous damage. The ROI_M was compared with an automatic ROI approach (ROI_A), where regions were automatically identified if the cpRNFL thickness fell below the 1% lower norma

SUBMITTER: Wu Z 

PROVIDER: S-EPMC5829954 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature