Diet during pregnancy and infancy and risk of allergic or autoimmune disease: A systematic review and meta-analysis.

ABSTRACT:

Background

There is uncertainty about the influence of diet during pregnancy and infancy on a child's immune development. We assessed whether variations in maternal or infant diet can influence risk of allergic or autoimmune disease.

Methods and findings

Two authors selected studies, extracted data, and assessed risk of bias. Grading of Recommendations Assessment, Development and Evaluation (GRADE) was used to assess certainty of findings. We searched Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica dataBASE (EMBASE), Web of Science, Central Register of Controlled Trials (CENTRAL), and Literatura Latino Americana em Ciências da Saúde (LILACS) between January 1946 and July 2013 for observational studies and until December 2017 for interventio

SUBMITTER: Garcia-Larsen V 

PROVIDER: S-EPMC5830033 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature