Nanostructured surface topographies have an effect on bactericidal activity.

ABSTRACT:

Background

Due to the increased emergence of antimicrobial resistance, alternatives to minimize the usage of antibiotics become attractive solutions. Biophysical manipulation of material surface topography to prevent bacterial adhesion is one promising approach. To this end, it is essential to understand the relationship between surface topographical features and bactericidal properties in order to develop antibacterial surfaces.

Results

In this work a systematic study of topographical effects on bactericidal activity of nanostructured surfaces is presented. Nanostructured Ormostamp polymer surfaces are fabricated by nano-replication technology using nanoporous templates resulting in 80-nm diameter nanopillars. Six Ormostamp surfaces with nanopillar arrays of various nanopil

SUBMITTER: Wu S 

PROVIDER: S-EPMC5830064 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature