Patient-Specific Flow Descriptors and Normalized wall index in Peripheral Artery Disease: a Preliminary Study.

ABSTRACT:

Background and aims

MRI-based hemodynamics have been applied to study the relationship between time-averaged wall shear stresses (TAWSS), oscillatory shear index (OSI) and atherosclerotic lesions in the coronary arteries, carotid artery, and human aorta. However, the role of TAWSS and OSI are poorly understood in lower extremity arteries. The aim of this work was to investigate the feasibility of hemodynamic assessment of the superficial femoral artery (SFA) in patients with peripheral artery disease (PAD) and we hypothesized that there is an association between TAWSS and OSI, respectively, and atherosclerotic burden expressed as the normalized wall index (NWI).

Methods

Six cases of 3D vascular geometries of the SFA and related inlet/outlet flow conditions were extracted fro

SUBMITTER: Singh J 

PROVIDER: S-EPMC5830147 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature