Association Between Treatment at High-Volume Facilities and Improved Overall Survival in Soft Tissue Sarcomas.

ABSTRACT: PURPOSE:Soft tissue sarcomas (STS) are rare malignancies that require complex multidisciplinary management. Therefore, facilities with high sarcoma case volume may demonstrate superior outcomes. We hypothesized that STS treatment at high-volume (HV) facilities would be associated with improved overall survival (OS). METHODS AND MATERIALS:Patients aged ≥18 years with nonmetastatic STS treated with surgery and radiation therapy at a single facility from 2004 through 2013 were identified from the National Cancer Database. Facilities were dichotomized into HV and low-volume (LV) cohorts based on total case volume over the study period. OS was assessed using multivariable Cox regression with propensity score-matching. Patterns of care were assessed using multivariable logistic regression analys

SUBMITTER: Venigalla S 

PROVIDER: S-EPMC5830163 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature