Aspirin use and ovarian cancer mortality in a Danish nationwide cohort study.

ABSTRACT:

Background

Increasing data suggest that aspirin use may improve cancer survival; however, the evidence is sparse for ovarian cancer.

Methods

We examined the association between postdiagnosis use of low-dose aspirin and mortality in a nationwide cohort of women with epithelial ovarian cancer between 2000 and 2012. Information on filled prescriptions of low-dose aspirin, dates and causes of death, and potential confounding factors was obtained from nationwide Danish registries. We used Cox regression models to estimate hazard ratios (HRs) with 95% confidence intervals (CIs) for ovarian cancer-specific or other-cause mortality associated with low-dose aspirin use.

Results

Among 4117 patients, postdiagnosis use of low-dose aspirin was associated with HRs of 1.02 (95% CI:

SUBMITTER: Verdoodt F 

PROVIDER: S-EPMC5830597 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature