Effects of complexity and seasonality on backward bifurcation in vector-host models.

ABSTRACT: We study implications of complexity and seasonality in vector-host epidemiological models exhibiting backward bifurcation. Vector-host diseases represent complex infection systems that can vary in the transmission processes and population stages involved in disease progression. Seasonal fluctuations in external forcing factors can also interact in a complex way with internal host factors to govern the transmission dynamics. In backward bifurcation, the insufficiency of R₀ < 1 for predicting the stability of the disease-free equilibrium (DFE) state arises due to existence of bistability (coexisting DFE and endemic equilibria) for a range of R₀ values below one. Here we report that this region of bistability decreases with increasing complexity of vector-b

SUBMITTER: Bilal S 

PROVIDER: S-EPMC5830785 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature