An informational view of accession rarity and allele specificity in germplasm banks for management and conservation.

ABSTRACT: Germplasm banks are growing in their importance, number of accessions and amount of characterization data, with a large emphasis on molecular genetic markers. In this work, we offer an integrated view of accessions and marker data in an information theory framework. The basis of this development is the mutual information between accessions and allele frequencies for molecular marker loci, which can be decomposed in allele specificities, as well as in rarity and divergence of accessions. In this way, formulas are provided to calculate the specificity of the different marker alleles with reference to their distribution across accessions, accession rarity, defined as the weighted average of the specificity of its alleles, and divergence, defined by the Kullback-Leibler formula. Albeit being d

SUBMITTER: Reyes-Valdes MH 

PROVIDER: S-EPMC5831390 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature