Association Between Ratio of Fresh Frozen Plasma to Red Blood Cells During Massive Transfusion and Survival Among Patients Without Traumatic Injury.

ABSTRACT:

Importance

Hemostatic resuscitation has been shown to be beneficial for patients with trauma, but there is little evidence that it is equally beneficial for bleeding patients without trauma. The practice of a high transfusion ratio of fresh frozen plasma (FFP) to red blood cells (RBCs) has spread to other surgical and medical fields.

Objective

To identify whether ratio-based resuscitation in patients without trauma is associated with improved survival.

Design, setting, and participants

This study is a retrospective review of all massive transfusions provided in an urban academic hospital from January 1, 2009, through December 31, 2012. Massive transfusion was defined as the transfusion of at least 10 U of RBCs in the first 24 hours after a patient's admission to the o

SUBMITTER: Mesar T 

PROVIDER: S-EPMC5831422 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature