Stereotactic ablative radiotherapy versus lobectomy for stage I non-small cell lung cancer: A systematic review.

ABSTRACT:

Background

There is debate regarding the use of stereotactic ablative radiotherapy (SABR) or surgery for patients with early stage non-small cell lung cancer (NSCLC). This meta-analysis compared the clinical efficacy of SABR and lobectomy in stage I NSCLC patients.

Methods

An online search identified eight eligible articles (including 2 trials and 7 cohort studies) for inclusion. The odds ratio (OR) was used as a summary statistic. Overall survival (OS), cause-specific survival (CSS), and recurrence-free survival (RFS) were selected to calculate ORs with 95% confidence intervals (CI). Fixed-effects or random-effects models were conducted according to study heterogeneity.

Results

There were no significant differences between SABR and lobectomy in terms of one-year OS o

SUBMITTER: Wang S 

PROVIDER: S-EPMC5832478 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature