Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.

ABSTRACT:

Background

The effect of age on asthma severity is poorly understood.

Objectives

The objective of this study was to compare the baseline features of severe and nonsevere asthma in the Severe Asthma Research Program (SARP) III cohort, and examine in cross section the effects of age on those features.

Methods

SARP III is a National Institutes of Health/National Heart Lung Blood Institute multisite 3-year cohort study conducted to investigate mechanisms of severe asthma. The sample included 188 children (111 severe, 77 nonsevere) and 526 adults (313 severe, 213 nonsevere) characterized for demographic features, symptoms, health care utilization, lung function, and inflammatory markers compared by age and severity.

Results

Compared with children with nonsevere asth

SUBMITTER: Teague WG 

PROVIDER: S-EPMC5832534 | biostudies-literature | 2018 Mar - Apr

REPOSITORIES: biostudies-literature