Evaluation of the expression and clinical value of lncRNA AC010761.9 in human gastric adenocarcinoma.

ABSTRACT:

Background

The current study determined the expression and clinical value of lncRNA AC010761.9 in human gastric adenocarcinoma (GA).

Methods

Real-time quantitative reverse transcription (qRT)-PCR was used to detect the level of lncRNA expression in 145 GA tissues and three GA cell lines, and the correlation between its level and clinicopathologic characteristics and potential corresponding mRNA of TNF receptor-associated factor 4 gene (TRAF4) was then evaluated.

Results

Elevated lncRNA AC010761.9 was detected in all 6 GA tissues by previous lncRNA expression profile microarray assay. LncRNA AC010761.9 was over-expressed in 99 of 145 GA tissues (68.3%) with an elevated fold change of up to 35.14 compared to matched paracancerous tissues (p < 0.05), and was also over-ex

SUBMITTER: Wang Z 

PROVIDER: S-EPMC5833146 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature