Relationships between psychological state, abuse, somatization and visceral pain sensitivity in irritable bowel syndrome.

ABSTRACT:

Background and objective

Psychological states may interfere with visceral sensitivity. Here we investigate associations between psychosocial factors and visceral sensitivity in irritable bowel syndrome (IBS).

Methods

Two IBS patient cohorts (Cohort 1: n = 231, Rome II; Cohort 2: n = 141, Rome III) underwent rectal barostat testing, and completed questionnaires for anxiety, depression, somatization, and abuse. The associations between questionnaire measures and visceral sensitivity parameters were analyzed in three-step general linear models (step1: demographic and abuse variables; step 2: anxiety and depression; step 3: somatization).

Results

Cohort 1. Pain threshold was positively associated with age and female gender, and negatively with adult sexual a

SUBMITTER: Grinsvall C 

PROVIDER: S-EPMC5833221 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature