Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study.

ABSTRACT:

Importance

The Roux-en-Y gastric bypass is effective in achieving established diabetes treatment targets, but durability is unknown.

Objective

To compare durability of Roux-en-Y gastric bypass added to intensive lifestyle and medical management in achieving diabetes control targets.

Design, setting, and participants

Observational follow-up of a randomized clinical trial at 4 sites in the United States and Taiwan, involving 120 participants who had a hemoglobin A1c (HbA1c) level of 8.0% or higher and a body mass index between 30.0 and 39.9 (enrolled between April 2008 and December 2011) were followed up for 5 years, ending in November 2016.

Interventions

Lifestyle-intensive medical management intervention based on the Diabetes Prevention Program and LookAHEAD tr

SUBMITTER: Ikramuddin S 

PROVIDER: S-EPMC5833547 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature