Association of Abnormal Renal Profiles and Proliferative Diabetic Retinopathy and Diabetic Macular Edema in an Asian Population With Type 2 Diabetes.

ABSTRACT:

Importance

The comorbidity of chronic kidney disease and diabetic retinopathy (DR) is well known. However, to our knowledge, no cohort study has demonstrated the effect of chronic kidney disease on the development or progression of DR.

Objective

To investigate the association of chronic kidney disease with the development of DR and diabetic macular edema (DME) in type 2 diabetes.

Design, setting, and participants

This 8-year prospective cohort study that was conducted in 2 medical centers in Taiwan included 2135 patients with type 2 diabetes.

Exposures

The baseline and mean follow-up renal profiles including serum creatinine level, estimated glomerular filtration rate (eGFR), and urinary albumin/creatinine ratio (ACR).

Main outcomes and measures

Diabetic

SUBMITTER: Hsieh YT 

PROVIDER: S-EPMC5833599 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature