Modeling individual and relative accuracy of screening tools in geriatric oncology.

ABSTRACT:

Background

Classification probabilities reflect to what degree a screening test represents the true disease state and include true positive (TPF) and false positive fractions (FPF). With two tests, one can compare TPF and FPF using relative probabilities which offer advantages in terms of interpretation and statistical modeling. Our objective was to highlight how individual and relative TPF and FPF can be easily estimated and compared within a regression modeling framework. This allows the modeling of tests' accuracy while adjusting for multiple covariates, and thus provides valuable information in addition to the crude TPF and FPF. We illustrate our purpose with the G8 and VES-13 screening tests aimed at identifying elderly cancer patients in need for a comprehensive geriatric ass

SUBMITTER: Bellera CA 

PROVIDER: S-EPMC5834042 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature