Long-term outcome of 487 patients with early-stage extra-nodal marginal zone lymphoma.

ABSTRACT:

Background

Localized early-stage extra-nodal marginal zone lymphoma (MZL) presents with heterogeneous organ involvement and is treated with various modalities, including resection, radiotherapy, and systemic therapy. We report the long-term outcome of a large cohort of extra-nodal MZL and assess the impact of patient and disease characteristics, organ site, and treatment strategy on disease control and survival.

Patients and methods

We identified 487 consecutive patients with stage IE or IIE MZL referred between 1992 and 2012 to Memorial Sloan Kettering Cancer Center. Pathology was reviewed by hematopathologists at our institution. Patient and disease factors as well as treatment types were analyzed for association with relapse-free survival, overall survival, and cumulative

SUBMITTER: Teckie S 

PROVIDER: S-EPMC5834123 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature