Borderline resectable pancreatic cancer: conceptual evolution and current approach to image-based classification.

ABSTRACT:

Background

Diagnostic imaging plays a critical role in the initial diagnosis and therapeutic monitoring of pancreatic adenocarcinoma. Over the past decade, the concept of 'borderline resectable' pancreatic cancer has emerged to describe a distinct subset of patients existing along the spectrum from resectable to locally advanced disease for whom a microscopically margin-positive (R1) resection is considered relatively more likely, primarily due to the relationship of the primary tumor with surrounding vasculature.

Materials and methods

This review traces the conceptual evolution of borderline resectability from a radiological perspective, including the debates over the key imaging criteria that define the thresholds between resectable, borderline resectable, and locally adva

SUBMITTER: Gilbert JW 

PROVIDER: S-EPMC5834155 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature