Clinical and inflammatory characteristics of Asthma-COPD overlap in workers with occupational asthma.

ABSTRACT:

Introduction

Although Asthma-COPD Overlap (ACO) has been described among populations of subjects with COPD or asthma, ACO has never been described among a population of subjects with occupational asthma (OA).

Objectives

The aims of this study were to: 1. identify ACO in a population of subjects with OA; and 2. compare the clinical characteristics between ACO and OA.

Methods

This retrospective study included all subjects diagnosed with OA between 2000 and 2017 in an OA referral center. Occupational Asthma-COPD Overlap (OACO) was defined as post-bronchodilator FEV1/FVC < 70% and smoking history ≥ 10 pack-years, along with a diagnosis of OA.

Results

Three hundred and four subjects were included, 262 (86.2%) were classified as OA and 42 (13.8%) as OACO. OA subjects

SUBMITTER: Ojanguren I 

PROVIDER: S-EPMC5834173 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature