Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors.

ABSTRACT:

Objectives

To determine the frequency of hyperoxia and hypocapnia during pediatric extracorporeal membrane oxygenation and their relationships to complications, mortality, and functional status among survivors.

Design

Secondary analysis of data collected prospectively by the Collaborative Pediatric Critical Care Research Network.

Setting

Eight Collaborative Pediatric Critical Care Research Network-affiliated hospitals.

Patients

Age less than 19 years and treated with extracorporeal membrane oxygenation.

Interventions

Hyperoxia was defined as highest PaO2 greater than 200 Torr (27 kPa) and hypocapnia as lowest PaCO2 less than 30 Torr (3.9 kPa) during the first 48 hours of extracorporeal membrane oxygenation. Functional status at hospital discharge was eva

SUBMITTER: Cashen K 

PROVIDER: S-EPMC5834382 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature