Retinal microvascular parameters are not associated with reduced renal function in a study of individuals with type 2 diabetes.

ABSTRACT: The eye provides an opportunistic "window" to view the microcirculation. There is published evidence of an association between retinal microvascular calibre and renal function measured by estimated glomerular filtration rate (eGFR) in individuals with diabetes mellitus. Beyond vascular calibre, few studies have considered other microvascular geometrical features. Here we report novel null findings for measures of vascular spread (vessel fractal dimension), tortuosity, and branching patterns and their relationship with renal function in type 2 diabetes over a mean of 3 years. We performed a nested case-control comparison of multiple retinal vascular parameters between individuals with type 2 diabetes and stable (non-progressors) versus declining (progressors) eGFR across two time points wit

SUBMITTER: McKay GJ 

PROVIDER: S-EPMC5834527 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature